Main Page

From AAAWiki

1 Info
2 Announcement and dataset freeze
- 2.1 Announcements
- 2.2 Datasets
3 Important Pages
4 Sequencing
5 Assembly
6 Annotation
7 Alignment
8 Chromosomal Maps
9 Analysis
10 Phylogeny
11 Tools
12 Papers
13 More Information

Info

Welcome to the AAA Wiki - created to coordinate the Assembly, Alignment and Annotation of the now 12 sequenced Drosophila genomes. Creating and editing pages on this Wiki requires registration.

The first main publications from these genomes sequences are now available

Drosophila 12 Genomes Consortium, 2007. Evolution of genes and genomes on the Drosophila phylogeny. Nature 450, 203-218 [1]

Stark et al., 2007. Discovery of functional elements in 12 Drosophila genomes using evolutionary signatures. Nature 450, 219-232 [2]

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Announcement and dataset freeze

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Announcements

12 Genomes Paper outline
Dmel Reannotation Paper outline

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Datasets

Protein coding genes
Noncoding RNA genes
Whole genome alignments

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Important Pages

Annotation Coordination - information on how to submit annotations.
Annotation Submission - list of submitted annotations.

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The 12 Drosophila genomes to be analyzed here include the published sequences of D. melanogaster and D. pseudoobscura, as well as 10 additional genomes sequenced in response to two community white papers. D. simulans and D. yakuba were sequenced by the Washington University Genome Center. D. erecta, D. ananassae, D. virilis, D. mojavensis and D. grimshawi were sequenced by Agencourt, Inc., D. willistoni was sequenced by the J. Craig Venter Institute, and D. persimilis and D. sechellia were sequenced to low coverage by the Broad Institute. Additional information about these species and their sequences can be found on the Species Pages.

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Assembly

The first complete set of assemblies of all 12 species was released in February 2006 as Comparative Analysis Freeze 1. Details on the assemblies can be found on the Assembly page.

Assembly Summaries

Although the assemblies have been frozen for the first round of papers, we would like to know if you find problems with the assemblies, which can be corrected in the next releases. Please post assembly problems here.

Assembly Problems

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Annotation

Several groups are already producing annotations based on the frozen assemblies, and additional groups are encouraged to participate in the annotation process. We will be producing a reconciled set of gene predictions in late spring, and will release all annotations as they are produced. For updated information on annotation plans see the Annotation and Annotation Coordination pages.

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