Evolution of sex and reproduction related genes
From AAAWiki
Civetta, Kulathinal, Singh and Wolfner labs.
Comparisons of rates of sequence divergence have shown a general pattern of rapid evolution in sex and reproduction related genes (Singh and Kulathinal 2000, Swanson and Vacquier 2002, Panhuis et al 2006). Most comparative genomics analyses however, have pooled a wide variety of genes into a single sex-related category and differences in rates across sex-specific functional classes have been overlooked. A vast amount of information is now available to conduct large-scale comparative genomics of functional relevance.
Alberto Civetta, Rob Kulathinal, Mariana Wolfner and Rama Singh (including Santosh Jagadeeshan and Wilfried Haerty), are interested in contributing on the evolution of sex and reproduction related genes. Within this broad framework, we have developed more specific topics that are outlined below.
- Rates of evolution of testis, ovary and head transcriptomes
- Rates of evolution of sex-specific functional categories (male-, female- biased, spermatogenesis, oogenesis, seminal proteins, etc)
- Rates of evolution of sex-specific genes on autosomes vs. sex chromosomes.
- Rates of evolution of genes misexpressed in hybrids.
We welcome other laboratories to join in our contribution on the evolution of sex and reproduction related genes.
